Acne Treatment Gel, 60 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Pack of 2) (Packaging May Vary)

4.5 / 5 (70,100 reviews)
Acne Treatment Gel, 60 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Pack of 2) (Packaging May Vary)

Product Description

Differin Gel is a dermatologist-recommended, over-the-counter acne treatment gel containing 0.1% Adapalene, a powerful retinoid. This 60-day supply pack includes two 15g tubes, providing a consistent and effective regimen to target stubborn acne at its source. It works by normalizing skin cell turnover and reducing inflammation to clear existing pimples, blackheads, and whiteheads while preventing new ones from forming. Formulated specifically for the face, it's a cornerstone treatment for those struggling with persistent acne.

This treatment is uniquely suited for acne-prone and sensitive skin. Unlike some harsh acne products, Differin Gel is designed to be effective yet gentle, minimizing irritation while delivering results. Its retinoid action helps unclog pores and smooth skin texture over time. The convenient 60-day supply ensures you have enough product to see the full benefits, as consistent use is key to achieving and maintaining clearer skin. It's a targeted solution for adults and adolescents seeking a clinically proven, non-antibiotic acne treatment.

Ideal for daily use, this gentle acne gel should be applied as a thin layer to clean, dry skin once daily. Users can incorporate it into their evening skincare routine. While it's effective for various acne types, it's particularly beneficial for those who have not found success with standard benzoyl peroxide or salicylic acid products. For best results and to manage potential initial dryness, pair it with a non-comedogenic moisturizer and a daily sunscreen, as retinoids can increase sun sensitivity. Explore our acne care category for complementary soothing moisturizers and cleansers.

Key Features:

  • TARGETS ACNE: Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
  • CLEARS, TREATS & PREVENTS: Differin works differently than other Acne treatments by normalizing skin cell turnover and effectively targets two primary causes of Acne, clogged pores and inflammation
  • RX STRENGTH ACNE RETINOID: Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
  • DERMATOLOGIST RECOMMENDED: Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating Acne
  • REAL RESULTS: In a clinical study, Differin gel provided up to 87 percent reduction in acne breakouts after 12 weeks, which will continue to improve with further use
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Reviews

Clinically Proven, Prescription-Strength Efficacy

The primary advantage of Differin Gel is its status as the first FDA-approved over-the-counter retinoid for acne. Its 0.1% Adapalene formula offers prescription-strength results without the need for a doctor's visit. Clinical studies demonstrate its ability to significantly reduce both inflammatory and non-inflammatory acne lesions. As a retinoid, it treats the root causes of acne—abnormal skin cell shedding and inflammation—rather than just superficially drying out pimples, leading to longer-lasting clear skin and improved skin texture.

Gentle Formula for Sensitive Skin

Many bestselling acne treatments are too harsh, causing redness, peeling, and discomfort that leads users to abandon their regimen. Differin Gel's popularity stems from its engineered gentleness. Its microsphere technology allows for slow release of the active ingredient, reducing potential irritation. This makes it a standout choice for individuals with sensitive skin who have previously struggled with other acne products. Users can effectively treat acne without compromising their skin's barrier, which is a key factor in its high user satisfaction and repeat purchase rates.

Excellent Value and Convenience

This product offers exceptional value as a 60-day supply. Buying in a twin-pack ensures continuity of treatment, which is critical for retinoid therapy where results build over 8-12 weeks. Compared to the cost and hassle of dermatologist appointments and prescription copays, this over-the-counter solution is both cost-effective and convenient. The packaging is travel-friendly and hygienic, with a tube that dispenses the perfect pea-sized amount needed for full-face coverage, minimizing waste and maximizing the product's lifespan.

Preventative and Corrective Action

Unlike spot treatments that only address existing breakouts, Differin Gel works as both a corrective and preventative treatment. Its daily use helps keep pores clear, preventing the formation of new comedones (clogged pores) that turn into pimples. This dual-action approach saves users from the frustrating cycle of treating one breakout only to face another. Over time, consistent use can lead to a sustained reduction in acne frequency and severity, giving users greater control over their skin's condition and boosting confidence.

While highly effective, Differin Gel is not a miracle overnight cure, and users must manage their expectations. The most common drawback is the potential "retinoid adjustment period" or "purge." During the first 2-6 weeks of use, some users experience increased dryness, peeling, redness, and a temporary worsening of acne as the product accelerates the skin's renewal process, bringing underlying clogs to the surface. This period can be discouraging and requires patience, consistent moisturizing, and sun protection to manage. It is not suitable for those seeking immediate results.

The product has specific suitability limitations. It is formulated for acne-prone skin and is not intended as an anti-aging treatment, although retinoids are known for such benefits. Differin Gel may be too strong for individuals with extremely sensitive skin, rosacea, or eczema, potentially causing severe irritation. It is also not recommended for use during pregnancy or breastfeeding without consulting a healthcare provider. Furthermore, it primarily targets microcomedones (the beginning of acne) and inflammatory acne; it may be less effective for severe cystic acne, which might require combined oral or stronger prescription therapies.

Successful use demands a committed skincare routine and lifestyle adjustments. Because Adapalene increases sun sensitivity, daily broad-spectrum sunscreen is non-negotiable; failure to use it can lead to sunburn and hyperpigmentation. The gel can be drying, so it must be paired with a gentle, non-foaming cleanser and a rich, non-comedogenic moisturizer—adding potential cost and steps to one's routine. It also cannot be used concurrently with other potentially irritating actives like benzoyl peroxide, salicylic acid, or physical scrubs without risking significant irritation, limiting skincare flexibility for some users.

Product Details

Is Discontinued By Manufacturer ‏ : ‎No
Product Dimensions ‏ : ‎4 x 5 x 7 inches; 1.06 ounces
Item model number ‏ : ‎0299.024060
Department ‏ : ‎Beauty & Personal Care
UPC ‏ : ‎302990240603
Manufacturer ‏ : ‎Galderma
ASIN ‏ : ‎B07HKVBRCF
Best Sellers Rank:#27 in Facial Masks
Customer Reviews:4.5 4.5 out of 5 stars

Differin Gel stands out as a top-tier, accessible solution for persistent acne. Its 0.1% Adapalene formula delivers prescription-strength efficacy in an over-the-counter package, making it a revolutionary option for millions. The key to its success is its dual ability to clear existing breakouts and prevent new ones by targeting the skin cell turnover process, all while being formulated to be gentler than many other retinoid options. For those with mild to moderate acne who have struggled with other treatments, it represents a clinically proven path to clearer skin.

We recommend Differin Gel primarily for adults and adolescents with acne-prone or sensitive skin who are prepared for a commitment. The ideal user is patient, understands the potential initial adjustment period, and is willing to adopt a supportive skincare routine including moisturizer and daily sunscreen. It is less recommended for those with severe cystic acne, very sensitive skin conditions like rosacea, or anyone seeking instant results. When used consistently as directed, this 60-day supply offers remarkable value and the potential for significant, long-term improvement in skin clarity and texture.

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